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Approaches to control - by example

In certain cases, the nature of the work means that the use of local exhaust ventilation and/or respiratory protective equipment would impact significantly on the ability to work safely. In such cases, the risk assessment for the work must justify not using these specific controls and specify clearly what other measures will be used to control exposure.

The following guidance is based on examples of actual activities carried out at UCL to help you decide on appropriate measures (this are in addition to general controls in registered rooms)

  • Limit the number of animals present in the room at any one time.
  • Direct handling eg preparatory work should be carried out in a defined area and using appropriate personal protective equipment and respiratory protective equipment - ideally any exposure prone procedures such as shaving/clipping of fur should be carried out in advance of moving the animal to a registered room (using LEV in a BSU).
  • Surgical procedures should be carried out in defined areas that are cleaned directly after use - PPE/RPE should be worn during surgery and the animal covered eg with disposable drapes which are disposed of after use.
  • Consider how to control exposure during longer experiments - for example:
    • Measures used to control light/temperature/humidity can also be used to control the spread of allergens, eg using curtains around experimental rigs, placing an animal in environmental control chambers, covering an animal with surgical drapes.
    • Working with animals under anaesthetic will limit movement and so liberation of allergens
    • If observation over long periods of time is needed, this could be done remotely eg using video cameras.


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